Recombinant Mouse C-C motif chemokine 6 protein (Ccl6)
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中文名稱：Recombinant Mouse C-C motif chemokine 6 protein(Ccl6) (Active)
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品名簡稱：Recombinant Mouse Ccl6 protein (Active)
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貨號：CSB-AP001251MO
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說明書：
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規(guī)格：￥2124
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圖片：
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其他：
產(chǎn)品詳情
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純度：>97% as determined by SDS-PAGE.
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內(nèi)毒素：Less than 1.0 EU/μg as determined by LAL method.
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生物活性：Fully biologically active when compared to standard. The biologically active determined by a chemotaxis bioassay using human CCR1 transfected murine BaF3 cells is in a concentration range of 10-100 ng/ml.
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基因名：Ccl6
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Uniprot No.：
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別名：Ccl6; C10; Scya6C-C motif chemokine 6; Protein C10; Small-inducible cytokine A6) [Cleaved into: CCL6(22-95); CCL6(23-95)]
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種屬：Mus musculus (Mouse)
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蛋白長度：Full Length of Mature Protein
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來源：E.Coli
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分子量：10.7 kDa
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表達(dá)區(qū)域：22-116aa
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氨基酸序列GLIQEIEKED RRYNPPIIHQ GFQDTSSDCC FSYATQIPCK RFIYYFPTSG GCIKPGIIFI SRRGTQVCAD PSDRRVQRCL STLKQGPRSG NKVIA
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蛋白標(biāo)簽：Tag-Free
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產(chǎn)品提供形式：Liquid or Lyophilized powder
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緩沖液：Lyophilized from a 0.2 μm filtered concentrated solution in 20 mM Tris, pH 8.0, 500 mM NaCl
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儲存條件：Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
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保質(zhì)期：The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C. -
貨期：5-10 business days
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Datasheet & COA：Please contact us to get it.
產(chǎn)品評價
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靶點詳情
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功能：CCL6(22-95) and CCL6(23-95) are potent chemoattractants.
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基因功能參考文獻(xiàn)：
- Mice lacking RXRalpha in myeloid cells exhibit reduced levels of CCL6 and CCL9, impaired recruitment of leukocytes to sites of inflammation, and lower susceptibility to sepsis. PMID: 20498053
- enhanced expression in intestinal epithelium following immunostimulation with LPS or pro-inflammatory cytokines PMID: 19812544
- the injury-induced expression of C10 at the mRNA and protein level PMID: 11895334
- c10 promotes fibrosis by recruiting macrophages in the inflammatory response to bleomycin in the lung PMID: 12356575
- CCL6 gene activation and production induced by SCF in the presence or absence of rather specific inhibitors for certain pathways demonstrated that the MEK/MAPK pathway but not the PI-3K pathway was crucial for the SCF-induced CCL6 gene activation. PMID: 17234680
- the chemokines CCL6 and CCL9 as genes prominently induced by the type I IFNs and ICSBP PMID: 19171873
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亞細(xì)胞定位：Secreted.
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蛋白家族：Intercrine beta (chemokine CC) family
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組織特異性：Expressed in myelopoietic bone marrow cultures stimulated by GM-CSF.
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數(shù)據(jù)庫鏈接：
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