AXIN1 Antibody
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								中文名稱:AXIN1兔多克隆抗體
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								貨號:CSB-PA828936
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								規格:¥1100
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								圖片:- 
														
														The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using CSB-PA828936(AXIN1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
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														The image on the left is immunohistochemistry of paraffin-embedded Human lung cancer tissue using CSB-PA828936(AXIN1 Antibody) at dilution 1/30, on the right is treated with synthetic peptide. (Original magnification: ×200)
 
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								其他:
產品詳情
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											Uniprot No.:
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											基因名:
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											宿主:Rabbit
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											反應種屬:Human,Mouse,Rat
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											免疫原:Synthetic peptide of Human AXIN1
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											免疫原種屬:Homo sapiens (Human)
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											標記方式:Non-conjugated
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											抗體亞型:IgG
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											純化方式:Antigen affinity purification
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											濃度:It differs from different batches. Please contact us to confirm it.
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											保存緩沖液:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
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											產品提供形式:Liquid
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											應用范圍:ELISA,IHC
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											推薦稀釋比:Application Recommended Dilution ELISA 1:2000-1:5000 IHC 1:25-1:100 
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											Protocols:
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											儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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											貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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											用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關產品
靶點詳情
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											功能:Component of the beta-catenin destruction complex required for regulating CTNNB1 levels through phosphorylation and ubiquitination, and modulating Wnt-signaling. Controls dorsoventral patterning via two opposing effects; down-regulates CTNNB1 to inhibit the Wnt signaling pathway and ventralize embryos, but also dorsalizes embryos by activating a Wnt-independent JNK signaling pathway. In Wnt signaling, probably facilitates the phosphorylation of CTNNB1 and APC by GSK3B. Likely to function as a tumor suppressor. Enhances TGF-beta signaling by recruiting the RNF111 E3 ubiquitin ligase and promoting the degradation of inhibitory SMAD7. Also component of the AXIN1-HIPK2-TP53 complex which controls cell growth, apoptosis and development. Facilitates the phosphorylation of TP53 by HIPK2 upon ultraviolet irradiation.
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											相關疾病:Hepatocellular carcinoma (HCC); Caudal duplication anomaly (CADUA)
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											亞細胞定位:Cytoplasm. Nucleus. Membrane. Cell membrane.
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											組織特異性:Ubiquitously expressed.
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											數據庫鏈接:
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