CKLF Antibody
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								中文名稱:CKLF兔多克隆抗體
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								貨號(hào):CSB-PA656806
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								規(guī)格:¥1090
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								圖片:
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								其他:
產(chǎn)品詳情
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											Uniprot No.:
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											基因名:CKLF
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											別名:CKLF; CKLF1; HSPC224; UNQ410/PRO772; Chemokine-like factor; C32
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											宿主:Rabbit
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											反應(yīng)種屬:Human
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											免疫原:Synthesized peptide derived from the C-terminal region of Human C32.
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											免疫原種屬:Homo sapiens (Human)
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											標(biāo)記方式:Non-conjugated
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											純化方式:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
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											濃度:It differs from different batches. Please contact us to confirm it.
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											保存緩沖液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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											產(chǎn)品提供形式:Liquid
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											應(yīng)用范圍:WB, ELISA
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											推薦稀釋比:Application Recommended Dilution WB 1:500-1:2000 ELISA 1:10000 
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											Protocols:
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											儲(chǔ)存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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											貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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											用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關(guān)產(chǎn)品
靶點(diǎn)詳情
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											功能:May play an important role in inflammation and regeneration of skeletal muscle. Partly inhibited by interleukin 10.; has chemotactic response in monocytes, neutrophils and lymphocytes. Binds CCR4.
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											基因功能參考文獻(xiàn):- Data indicate that leukocyte-infiltrate derived chemokine-like factor (CKLF) expression is a candidate biomarker of favorable prognosis. PMID: 27153559
- CKLF1 expression was up-regulated in synovim from rheumatoid arthritis and ankylosing spondylitis patients. PMID: 26838743
- expression elevated in the skin of keloid patients PMID: 26986142
- role in the pathogenesis of psoriasis by promoting the proliferation of microvascular endothelial cells PMID: 25915746
- Chemokine-like factor 1 is over-expressed in patients with atopic dermatitis. PMID: 23983609
- CKLF1 can induce proliferation and inhibit apoptosis of human vascular smooth muscle cell through the down-regulation of Bax and Caspase-3 and the up-regulation of Bcl-2 expression. PMID: 23253812
- The expression of CKLF1 is up-regulated in atherosclerotic plaques. PMID: 20137403
- CKLF1-C19 and -C27 can stimulate antigen-presenting capability of dendritic cells PMID: 20392439
- CKLF1 could increase the proliferation of human bone marrow hematopoietic progenitor cells and colony formation PMID: 12411060
- Results confirm that the secreted peptides of CKLF1, C27 and C19, have functional activation via CCR4. PMID: 18069042
- Chemokine-like factor expression is differentially regulated in myoblasts and myotubes and thrombin could be a strong regulator for its expression PMID: 18294340
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											亞細(xì)胞定位:[Isoform 1]: Secreted.; [Isoform 2]: Membrane; Multi-pass membrane protein.; [Isoform 4]: Membrane; Multi-pass membrane protein.
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											蛋白家族:Chemokine-like factor family
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											組織特異性:Isoform 1, isoform 2, isoform 3 and isoform 4 have highest expression levels in adult spleen, lung, testis, ovary, peripheral blood leukocyte, placenta, pancreas, and in fetal brain, skeletal muscle, thymus and heart. Lower expression levels in adult skel
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