CLCF1 Antibody
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								中文名稱:CLCF1兔多克隆抗體
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								貨號:CSB-PA906951
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								規格:¥1090
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								圖片:
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								其他:
產品詳情
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											Uniprot No.:
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											基因名:CLCF1
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											別名:B cell stimulating factor 3 antibody; B-cell-stimulating factor 3 antibody; BSF 3 antibody; BSF-3 antibody; BSF3 antibody; Cardiotrophin like cytokine antibody; Cardiotrophin like cytokine factor 1 antibody; Cardiotrophin-like cytokine factor 1 antibody; CISS 2 antibody; CISS2 antibody; CLC antibody; CLCF 1 antibody; Clcf1 antibody; CLCF1_HUMAN antibody; Cold induced sweating syndrome 2 antibody; CRLF 1 associated cytokine like factor 1 antibody; CRLF1 associated cytokine like factor 1 antibody; Neurotrophin 1 antibody; Neurotrophin 1/B cell stimulating factor 3 antibody; Neurotrophin1 antibody; NNT 1 antibody; NNT-1 antibody; Novel neurotrophin 1 antibody; Novel neurotrophin-1 antibody; NR 6 antibody; NR6 antibody
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											宿主:Rabbit
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											反應種屬:Human,Mouse,Rat
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											免疫原:Synthetic peptide from Human protein at AA range: 171-220
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											免疫原種屬:Homo sapiens (Human)
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											標記方式:Non-conjugated
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											純化方式:The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen.
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											濃度:It differs from different batches. Please contact us to confirm it.
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											保存緩沖液:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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											產品提供形式:Liquid
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											應用范圍:IHC,ELISA
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											推薦稀釋比:Application Recommended Dilution IHC IHC-p:1:50-300 ELISA 1:10000-20000 
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											Protocols:
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											儲存條件:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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											貨期:Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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											用途:For Research Use Only. Not for use in diagnostic or therapeutic procedures.
相關產品
靶點詳情
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											功能:In complex with CRLF1, forms a heterodimeric neurotropic cytokine that plays a crucial role during neuronal development (Probable). Also stimulates B-cells. Binds to and activates the ILST/gp130 receptor.
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											基因功能參考文獻:- CLF-1, based on its binding site for CLC and on two additional and independent sites for CNTFRalpha and sorLA, is a key player in CLC and CNTFRalpha signaling and turnover. PMID: 26858303
- Cardiotrophin-like cytokine factor 1 (CLCF1) and neuropoietin (NP) signalling and their roles in development, adulthood, cancer and degenerative disorders. PMID: 26198769
- albuminuria in focal segmental glomerulosclerosis is related to qualitative or quantitative changes in the CLCF1-CRLF1 complex. PMID: 25843671
- activation of the Jak-STAT cascade is essential for corticotroph NNT-1/BSF-3 signaling. PMID: 12639901
- Structural and docking interaction studies showed that the R197L substitution destabilized the contact site between CLC and CNTFRalpha. PMID: 16782820
- Ciliary neurotrophic factor, cardiotrophin-like cytokine, and neuropoietin share a conserved binding site on the ciliary neurotrophic factor receptor alpha chain PMID: 18728012
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											相關疾病:Cold-induced sweating syndrome 2 (CISS2)
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											亞細胞定位:Secreted.
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											蛋白家族:IL-6 superfamily
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											組織特異性:Expressed predominantly in lymph nodes, spleen, peripheral blood lymphocytes, bone marrow, and fetal liver.
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											數據庫鏈接:
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