CLYBL Antibody
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中文名稱：CLYBL兔多克隆抗體
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貨號：CSB-PA005598GA01HU
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規格：￥3,900
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其他：
產品詳情
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Uniprot No.：
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基因名：CLYBL
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別名：CLYBL antibody; CLB antibody; Citramalyl-CoA lyase antibody; mitochondrial antibody; EC 4.1.3.25; antibody; 3S)-malyl-CoA thioesterase antibody; EC 3.1.2.30 antibody; Beta-methylmalate synthase antibody; EC 2.3.3.- antibody; Citrate lyase subunit beta-like protein antibody; Citrate lyase beta-like antibody; Malate synthase antibody; EC 2.3.3.9 antibody
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宿主：Rabbit
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反應種屬：Human,Mouse,Rat
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免疫原：Human CLYBL
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免疫原種屬：Homo sapiens (Human)
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抗體亞型：IgG
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純化方式：Antigen Affinity purified
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濃度：It differs from different batches. Please contact us to confirm it.
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保存緩沖液：PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
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產品提供形式：Liquid
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應用范圍：ELISA,WB,IHC
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Protocols：
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儲存條件：Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
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貨期：Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
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用途：For Research Use Only. Not for use in diagnostic or therapeutic procedures.
產品評價
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靶點詳情
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功能：Mitochondrial citramalyl-CoA lyase indirectly involved in the vitamin B12 metabolism. Converts citramalyl-CoA into acetyl-CoA and pyruvate in the C5-dicarboxylate catabolism pathway. The C5-dicarboxylate catabolism pathway is required to detoxify itaconate, a vitamin B12-poisoning metabolite. Also acts as a malate synthase in vitro, converting glyoxylate and acetyl-CoA to malate. Also displays malyl-CoA thioesterase activity. Also acts as a beta-methylmalate synthase in vitro, by mediating conversion of glyoxylate and propionyl-CoA to beta-methylmalate. Also has very weak citramalate synthase activity in vitro.
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基因功能參考文獻：
- Study reports that CLYBL loss leads to a cell-autonomous defect in the mitochondrial B12 metabolism and that itaconyl-CoA is a cofactor-inactivating, substrate-analog inhibitor of the mitochondrial B12-dependent methylmalonyl-CoA mutase PMID: 29056341
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亞細胞定位：Mitochondrion.
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蛋白家族：HpcH/HpaI aldolase family, Citrate lyase beta subunit-like subfamily
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數據庫鏈接：
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