HNRNPLL Antibody, FITC conjugated

說明書

產品詳情

產品名稱：

Rabbit anti-Homo sapiens (Human) HNRNPLL Polyclonal antibody
Uniprot No.：

Q8WVV9
基因名：

HNRNPLL
別名：

BLOCK24 antibody; Heterogeneous nuclear ribonucleoprotein L like antibody; Heterogeneous nuclear ribonucleoprotein L-like antibody; HNRLL_HUMAN antibody; hnRNPLL antibody; HNRPLL antibody; SRRF antibody; Stromal RNA regulating factor antibody; Stromal RNA-regulating factor antibody
宿主：

Rabbit
反應種屬：

Human
免疫原：

Recombinant Human Heterogeneous nuclear ribonucleoprotein L-like protein (1-72AA)
免疫原種屬：

Homo sapiens (Human)
標記方式：

FITC
克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

RNA-binding protein that functions as regulator of alternative splicing for multiple target mRNAs, including PTPRC/CD45 and STAT5A. Required for alternative splicing of PTPRC.
基因功能參考文獻：
1. Loss-of-function mutation of hnRNPLL disrupts peripheral T cell accumulation even in the absence of CD45 protein, indicating that hnRNPLL acts through an independent mechanism to promote peripheral T cell longevity. PMID: 20505149
2. Participation of SRRF (Stromal RNA Regulating Factor) isoforms in post-transcriptional events in bone marrow stromal cells; an important role in regulation of the RNA expression that directs the bone marrow stromal cells differentiation pathway PMID: 15256261
3. identification of heterogeneous ribonucleoprotein L-like (hnRNPLL) as a critical inducible regulator of CD45 alternative splicing PMID: 18669861
4. These data establish that hnRNP LL plays a critical and unique role in the signal-induced regulation of CD45 and demonstrate the utility of cell-based screens for the identification of novel splicing regulatory factors. PMID: 18719244
組織特異性：

Widely expressed. Detected in bone marrow stroma cells, skeletal muscle, heart, placenta, pancreas, kidney and lung.
數據庫鏈接：

HGNC: 25127

OMIM: 611208

KEGG: hsa:92906

STRING: 9606.ENSP00000387088

UniGene: Hs.445497

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