IL12B Antibody

Name: IL12B Antibody
Brand: CUSABIO
SKU: CSB-PA011587YA01SH

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說明書

產品詳情

產品名稱：

Rabbit anti-Sheep IL12B Polyclonal antibody
Uniprot No.：

P68220
基因名：

IL12B
別名：

IL12B antibody; Interleukin-12 subunit beta antibody; IL-12B antibody; Cytotoxic lymphocyte maturation factor 40 kDa subunit antibody; CLMF p40 antibody; IL-12 subunit p40 antibody
宿主：

Rabbit
反應種屬：

Sheep
免疫原：

Recombinant Sheep Interleukin-12 subunit beta protein (23-327AA)
免疫原種屬：

Sheep

標記方式：

Non-conjugated

本頁面中的產品，IL12B Antibody (CSB-PA011587YA01SH)，的標記方式是Non-conjugated。對于IL12B Antibody，我們還提供其他標記。見下表：

標記方式	貨號	產品名稱	應用
HRP	CSB-PA011587YB01SH	IL12B Antibody, HRP conjugated	ELISA
FITC	CSB-PA011587YC01SH	IL12B Antibody, FITC conjugated
Biotin	CSB-PA011587YD01SH	IL12B Antibody, Biotin conjugated	ELISA

克隆類型：

Polyclonal
抗體亞型：

IgG
純化方式：

>95%, Protein G purified
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
產品提供形式：

Liquid
應用范圍：

ELISA, WB, IHC

推薦稀釋比：

Application	Recommended Dilution
WB	1:500-1:2000
IHC	1:20-1:200

Protocols：

ELISA Protocol
Western Blotting (WB) Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated killer cells, and stimulate the production of IFN-gamma by resting PBMC.; Associates with IL23A to form the IL-23 interleukin, a heterodimeric cytokine which functions in innate and adaptive immunity. IL-23 may constitute with IL-17 an acute response to infection in peripheral tissues. IL-23 binds to a heterodimeric receptor complex composed of IL12RB1 and IL23R, activates the Jak-Stat signaling cascade, stimulates memory rather than naive T-cells and promotes production of proinflammatory cytokines. IL-23 induces autoimmune inflammation and thus may be responsible for autoimmune inflammatory diseases and may be important for tumorigenesis.
基因功能參考文獻：
1. The aim of the study was to assess the prognostic significance of Tumor Necrosis Factor-alpha, Interleukin-12(p40), Interleukin-6 and Interleukin 10 levels in cerebrospinal fluid (CSF) in sheep with encephalitic listeriosis. PMID: 25817420
2. Local intraocular production of IL-12 p40 (but not IL-4) prolongs corneal graft survival significantly PMID: 16081789
亞細胞定位：

Secreted.
蛋白家族：

Type I cytokine receptor family, Type 3 subfamily
數據庫鏈接：

KEGG: oas:443472

UniGene: Oar.721

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