STK17A Antibody

說明書

中文名稱：

STK17A兔多克隆抗體
貨號：

CSB-PA204025
規(guī)格：

￥1100
圖片：
The image on the left is immunohistochemistry of paraffin-embedded Human gastic cancer tissue using CSB-PA204025(STK17A Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)

The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using CSB-PA204025(STK17A Antibody) at dilution 1/15, on the right is treated with synthetic peptide. (Original magnification: ×200)
其他：

產(chǎn)品詳情

Uniprot No.：

Q9UEE5
基因名：

STK17A
別名：

DAP kinase-related apoptosis-inducing protein kinase 1 antibody; death-associated protein kinase-related 1 antibody; DRAK1 antibody; EC 2.7.11.1 antibody; Serine / threonine kinase 17a death associated protein kinase related 1 antibody; Serine/threonine kinase 17a antibody; Serine/threonine protein kinase 17a antibody; Serine/threonine-protein kinase 17A antibody; ST17A_HUMAN antibody; STK17 A antibody; STK17A antibody
宿主：

Rabbit
反應(yīng)種屬：

Human
免疫原：

Synthetic peptide of Human STK17A
免疫原種屬：

Homo sapiens (Human)
標(biāo)記方式：

Non-conjugated
抗體亞型：

IgG
純化方式：

Antigen affinity purification
濃度：

It differs from different batches. Please contact us to confirm it.
保存緩沖液：

-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol
產(chǎn)品提供形式：

Liquid
應(yīng)用范圍：

ELISA,IHC

推薦稀釋比：

Application	Recommended Dilution
ELISA	1:1000-1:2000
IHC	1:25-1:100

Protocols：

ELISA Protocol
Immunohistochemistry (IHC) Protocol
儲存條件：

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.
貨期：

Basically, we can dispatch the products out in 1-3 working days after receiving your orders. Delivery time maybe differs from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
用途：

For Research Use Only. Not for use in diagnostic or therapeutic procedures.

功能：

Acts as a positive regulator of apoptosis. Also acts as a regulator of cellular reactive oxygen species.
基因功能參考文獻(xiàn)：
1. These findings suggest that DRAK1 translocates in response to stimuli and induces apoptosis through its interaction with specific binding partners, p53 and/or ANT2. PMID: 29397938
2. the present study was the first to find localization of STK17A in normal bile canaliculi. PMID: 26305096
3. DRAK1 was predominantly localized in the cytoplasm and bound to Smad3, thereby interrupting Smad3/Smad4 complex formation, which is the core process for the induction of tumor suppressor genes by TGF-beta1 PMID: 25531329
4. STK17A provides a proliferative and survival advantage to GBM cells PMID: 24312360
5. When analyzing STK17A haplotypes distribution, we found association between TGGTC, TAGTC and AAGAT haplotypes and risk to develop SLE PMID: 23860322
6. identified STK17A as a novel direct target of p53 and a modulator of cisplatin toxicity and reactive oxygen species in testicular cancer cells. PMID: 21489989
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亞細(xì)胞定位：

Nucleus.
蛋白家族：

Protein kinase superfamily, CAMK Ser/Thr protein kinase family, DAP kinase subfamily
組織特異性：

Highly expressed in placenta. Lower levels in heart, lung, skeletal muscle, kidney and pancreas.
數(shù)據(jù)庫鏈接：

HGNC: 11395

OMIM: 604726

KEGG: hsa:9263

STRING: 9606.ENSP00000319192

UniGene: Hs.709489

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