Recombinant Pig Angiopoietin-2 (ANGPT2)

中文名稱：

Recombinant Pig Angiopoietin-2(ANGPT2)
貨號：

CSB-YP859369PI
規格：
來源：

Yeast
其他：

中文名稱：

Recombinant Pig Angiopoietin-2(ANGPT2)
貨號：

CSB-EP859369PI-B
規格：
來源：

E.coli
共軛：

Avi-tag Biotinylated
E. coli biotin ligase (BirA) is highly specific in covalently attaching biotin to the 15 amino acid AviTag peptide. This recombinant protein was biotinylated in vivo by AviTag-BirA technology, which method is BriA catalyzes amide linkage between the biotin and the specific lysine of the AviTag.
其他：

中文名稱：

Recombinant Pig Angiopoietin-2(ANGPT2)
貨號：

CSB-BP859369PI
規格：
來源：

Baculovirus
其他：

中文名稱：

Recombinant Pig Angiopoietin-2(ANGPT2)
貨號：

CSB-MP859369PI
規格：
來源：

Mammalian cell
其他：

產品詳情
產品評價
相關產品
靶點詳情

產品詳情

純度：

>85% (SDS-PAGE)
基因名：

ANGPT2
Uniprot No.：

Q9BDY7
別名：

ANGPT2Angiopoietin-2; ANG-2
種屬：

Sus scrofa (Pig)
蛋白長度：

Full Length of Mature Protein
表達區域：

19-496
氨基酸序列

YN NFRKSMDSTG KRQYQVQHGP CSYTFLLPET DNCRSPSSSY VSNAVQRDAP LDYDDSVRRL QVLENIMENN TQWLMKLESY IQDNMKKEMV EIQQNAVQNQ TAVMIEIGTN LLNQTAEQTR KLTDVEAQVL NQTTRLELQL LEHSLSTNKL EKQILDQTSE INKLQDKNSF LEKKVLDMED KHIVQLQSIK EEKDQLQVLV SKQNSIIEEL EKQLVTATVN NSVLQKQQHD LMETVHNLLT MISTSNSAKH SLVAKEEQII FRDCAEAFKS GLTTSGTYTL TFPNSTEETK AYCDMETGGG GWTVIQRRED GSVDFQRTWK EYKMGFGSPS GEHWLGNEFV SQVTNQKRYV LKIHLRDWEG NEAYSLYEHF YLSSEEFNYR IHLKGLTGTA GKISSISQPG NDFSTKDADN DKCICKCSQM LTGGWWFDAC GPSNLNGMYY PQRQNTNKFN GIKWYYWKGS GYSLKATTMM IRPADF
蛋白標簽：

Tag?type?will?be?determined?during?the?manufacturing?process.

The tag type will be determined during production process. If you have specified tag type, please tell us and we will develop the specified tag preferentially.
產品提供形式：

Lyophilized powder
Note: We will preferentially ship the format that we have in stock, however, if you have any special requirement for the format, please remark your requirement when placing the order, we will prepare according to your demand.
復溶：

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Please reconstitute protein in deionized sterile water to a concentration of 0.1-1.0 mg/mL.We recommend to add 5-50% of glycerol (final concentration) and aliquot for long-term storage at -20℃/-80℃. Our default final concentration of glycerol is 50%. Customers could use it as reference.
儲存條件：

Store at -20°C/-80°C upon receipt, aliquoting is necessary for mutiple use. Avoid repeated freeze-thaw cycles.
保質期：

The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself.
Generally, the shelf life of liquid form is 6 months at -20°C/-80°C. The shelf life of lyophilized form is 12 months at -20°C/-80°C.
貨期：

Delivery time may differ from different purchasing way or location, please kindly consult your local distributors for specific delivery time.
Note: All of our proteins are default shipped with normal blue ice packs, if you request to ship with dry ice, please communicate with us in advance and extra fees will be charged.
注意事項：

Repeated freezing and thawing is not recommended. Store working aliquots at 4°C for up to one week.
Datasheet ：

Please contact us to get it.

產品評價

靶點詳情

功能：

Binds to TEK/TIE2, competing for the ANGPT1 binding site, and modulating angiogenic signals mediated by ANGPT1. Can induce tyrosine phosphorylation of TEK/TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2-mediated loosening of cell-matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a permissive angiogenic signal.
基因功能參考文獻：
1. expression of angiopoietin 2 in the porcine metanephric kidney was observed in the podocytes of early developing glomeruli, but not in the cells near the glomerular hilus PMID: 20598355
2. ANGPT2 remained upregulated during maturation of glomeruli, which may be explained by the continuous growth of the glomeruli, as observed by stereological examination. PMID: 20713984
亞細胞定位：

Secreted.
數據庫鏈接：

KEGG: ssc:396730

STRING: 9823.ENSSSCP00000016694

UniGene: Ssc.240