TRIM24
Transcription intermediary factor 1-alpha is a protein in humans that is encoded by TRIM24 gene. Transcriptional coactivator that interacts with numerous nuclear receptors and coactivators and modulates the transcription of target genes. Interacts with chromatin depending on histone H3 modifications, having the highest affinity for histone H3 that is both unmodified at 'Lys-4' (H3K4me0) and acetylated at 'Lys-23' (H3K23ac). Has E3 protein-ubiquitin ligase activity. Promotes ubiquitination and proteasomal degradation of p53/TP53. Plays a role in the regulation of cell proliferation and apoptosis, at least in part via its effects on p53/TP53 levels. Up-regulates ligand-dependent transcription activation by AR, GCR/NR3C1, thyroid hormone receptor (TR) and ESR1.
TRIM24 Antibodies
TRIM24 for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 種屬反應性 | 應用類型 |
|---|---|---|---|
| CSB-PA024460GA01HU | TRIM24 Antibody | Human,Mouse,Rat | ELISA,WB,IHC |
| CSB-PA194059 | TRIM24 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA004291 | TRIM24 Antibody | Human,Mouse | WB, IHC, ELISA |
| CSB-PA172074 | TRIM24 Antibody | Human,Mouse | ELISA,WB |
| CSB-PA197772 | TRIM24 Antibody | Human,Mouse | ELISA,WB,IHC |
| CSB-PA024460LA01HU | TRIM24 Antibody | Human | ELISA |
| CSB-PA024460LD01HU | TRIM24 Antibody, Biotin conjugated | Human | ELISA |
| CSB-PA024460LC01HU | TRIM24 Antibody, FITC conjugated | Human | |
| CSB-PA024460LB01HU | TRIM24 Antibody, HRP conjugated | Human | ELISA |
TRIM24 Proteins
TRIM24 Proteins for Homo sapiens (Human)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP024460HU | Recombinant Human Transcription intermediary factor 1-alpha (TRIM24), partial | Yeast |
| CSB-EP024460HU | Recombinant Human Transcription intermediary factor 1-alpha (TRIM24), partial | E.coli |
| CSB-BP024460HU CSB-MP024460HU CSB-EP024460HU-B |
Recombinant Human Transcription intermediary factor 1-alpha (TRIM24), partial | Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TRIM24 Proteins for Mus musculus (Mouse)
| 產品貨號 | 產品名稱 | 來源 |
|---|---|---|
| CSB-YP720647MO CSB-EP720647MO CSB-BP720647MO CSB-MP720647MO CSB-EP720647MO-B |
Recombinant Mouse Transcription intermediary factor 1-alpha (Trim24), partial | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
