TXK
Tyrosine-protein kinase TXK is a protein in humans that is encoded by TXK gene. Non-receptor tyrosine kinase that plays a redundant role with ITK in regulation of the adaptive immune response. Regulates the development, function and differentiation of conventional T-cells and nonconventional NKT-cells. When antigen presenting cells (APC) activate T-cell receptor (TCR), a series of phosphorylation lead to the recruitment of TXK to the cell membrane, where it is phosphorylated at Tyr-420. Phosphorylation leads to TXK full activation. Contributes also to signaling from many receptors and participates in multiple downstream pathways, including regulation of the actin cytoskeleton. Like ITK, can phosphorylate PLCG1, leading to its localization in lipid rafts and activation, followed by subsequent cleavage of its substrates.
TXK Antibodies
TXK for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 種屬反應(yīng)性 | 應(yīng)用類型 |
|---|---|---|---|
| CSB-PA025362GA01HU | TXK Antibody | Human | ELISA,IHC,IF |
| CSB-PA060033 | TXK Antibody | Human | IHC, ELISA |
| CSB-PA025362LA01HU | TXK Antibody | Human, Rat | ELISA, WB, IHC, IF |
| CSB-PA025362LB01HU | TXK Antibody, HRP conjugated | Human | ELISA |
| CSB-PA025362LC01HU | TXK Antibody, FITC conjugated | Human | |
| CSB-PA025362LD01HU | TXK Antibody, Biotin conjugated | Human | ELISA |
TXK Proteins
TXK Proteins for Homo sapiens (Human)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP025362HU CSB-EP025362HU CSB-BP025362HU CSB-MP025362HU CSB-EP025362HU-B |
Recombinant Human Tyrosine-protein kinase TXK (TXK) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
TXK Proteins for Mus musculus (Mouse)
| 產(chǎn)品貨號 | 產(chǎn)品名稱 | 來源 |
|---|---|---|
| CSB-YP025362MO CSB-EP025362MO CSB-BP025362MO CSB-MP025362MO CSB-EP025362MO-B |
Recombinant Mouse Tyrosine-protein kinase TXK (Txk) | Yeast E.coli Baculovirus Mammalian cell In Vivo Biotinylation in E.coli |
